Membrane Lipid Reshaping Underlies Oxidative Stress Sensing by the Mitochondrial Proteins UCP1 and ANT1

• मुख्य लेखकों: Olga Jovanović (लेखक), Ksenia Chekashkina (लेखक), Sanja Škulj (लेखक), Kristina Žuna (लेखक), Mario Vazdar (लेखक), Pavel V. Bashkirov (लेखक), Elena E. Pohl (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Oxidative stress and ROS are important players in the pathogenesis of numerous diseases. In addition to directly altering proteins, ROS also affects lipids with negative intrinsic curvature such as phosphatidylethanolamine (PE), producing PE adducts and lysolipids. The formation of PE adducts potent...