Hypoxic-preconditioned mesenchymal stem cell-derived small extracellular vesicles inhibit neuronal death after spinal cord injury by regulating the SIRT1/Nrf2/HO-1 pathway

BackgroundOxidative stress and apoptosis of neurons significantly contribute to the pathophysiological cascade of spinal cord injury (SCI). However, the role of hypoxic-preconditioned mesenchymal stem cell-derived small extracellular vesicles (H-sEVs) in promoting SCI repair remains unclear. Hence,...

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Main Authors: Jian Rao (Author), Haishu Xie (Author), Zeyan Liang (Author), Zhelun Yang (Author), Pingping Chen (Author), Maochao Zhou (Author), Xiongjie Xu (Author), Yike Lin (Author), Fabin Lin (Author), Rui Wang (Author), Chunhua Wang (Author), Chunmei Chen (Author)
Format: Book
Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
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