Identification of novel AKT1 inhibitors from Sapria himalayana bioactive compounds using structure-based virtual screening and molecular dynamics simulations

• Main Authors: Laldinfeli Ralte (Author), Hmingremhlua Sailo (Author), Rakesh Kumar (Author), Laldinliana Khiangte (Author), Nachimuthu Senthil Kumar (Author), Yengkhom Tunginba Singh (Author)
• Format: Book
• Published: BMC, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Through the experimental and computational analyses, the present study sought to elucidate the chemical composition and anticancer potential of Sapria himalayana plant extract (SHPE). An in vitro analysis of the plant extract was carried out to determine the anticancer potential. Further, n...