Preclinical Safety Assessment of Antineoplastic Agents Based on Live Non-Pathogenic Enteroviruses

• Main Authors: K. V. Sivak (Author), K. I. Stosman (Author), E. Yu. Kalinina (Author), M. M. Lyubishin (Author), Ya. R. Orshanskaya (Author), T. N. Savateeva-Lyubimova (Author), S. B. Kazakova (Author), D. M. Fedoseeva (Author), A. S. Nazarov (Author), E. I. Radion (Author), S. M. Yudin (Author), A. A. Keskinov (Author), V. V. Makarov (Author), V. S. Yudin (Author), A. O. Zheltukhin (Author), P. O. Vorobyev (Author), D. V. Kochetkov (Author), G. V. Ilyinskaya (Author), A. V. Lipatova (Author), P. M. Chumakov (Author)
• Format: Book
• Published: Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products», 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

INTRODUCTION. Developing novel medicines based on non-pathogenic enterovirus strains exhibiting oncotropic and oncolytic properties represents an up-to-date and safe approach to complex cancer treatment and postoperative metastasis prevention. Safety pharmacology studies are a necessary step in the...