Interleukin-4 (IL-4) enhances and soluble interleukin-4 receptor (sIL-4R) inhibits histamine release from peripheral blood basophils and mast cells in vitro and in vivo

• Egile Nagusiak: B. Niggemann (Egilea), T. Zuberbier (Egilea), U. Herz (Egilea), K. Enssle (Egilea), U. Wahn (Egilea), H. Renz (Egilea)
• Formatua: Liburua
• Argitaratua: Hindawi Limited, 1997-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The aim of the study was to analyse the effect of interleukin-4 (IL-4) on allergen and anti-IgE mediated histamine release from basophils and human skin mast cells and to assess whether soluble recombinant interleukin-4 receptor (sIL4R) can inhibit these effects. Anti-IgE stimulated histamine releas...