Removal of HIV DNA by CRISPR from Patient Blood Engrafts in Humanized Mice
We used NOD/SCID mice, also known as NRG, to assess the ability of lentivirus-mediated intravenous delivery of CRISPR in editing the HIV-1 genome from the circulating PBMC engrafts, some of which homed within several animal solid tissues. Lentivirus-mediated delivery of a multiplex of guide RNAs acc...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2018-09-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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