Determination of Chemical Irritation Potential Using a Defined Gene Signature Set on Tissue-Engineered Human Skin Equivalents

• Main Authors: Amy L. Harding (Author), Craig Murdoch (Author), Simon Danby (Author), Md Zobaer Hasan (Author), Hirofumi Nakanishi (Author), Tetsuo Furuno (Author), Sirwan Hadad (Author), Robert Turner (Author), Helen E. Colley (Author)
• Format: Book
• Published: Elsevier, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There are no physical or visual manifestations that define skin sensitivity or irritation; a subjective diagnosis is made on the basis of the evaluation of clinical presentations, including burning, prickling, erythema, and itching. Adverse skin reaction in response to topically applied products is...