Mild Electrical Stimulation Increases Ubiquitinated Proteins and Hsp72 in A549 Cells via Attenuation of Proteasomal Degradation

• मुख्य लेखकों: Saori Morino (लेखक), Mary Ann Suico (लेखक), Tatsuya Kondo (लेखक), Erika Sekimoto (लेखक), Shuichiro Yano (लेखक), Tomoko Matsuda (लेखक), Takashi Matsuno (लेखक), Tsuyoshi Shuto (लेखक), Eiichi Araki (लेखक), Hirofumi Kai (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2008-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

To explore the cellular effects of mild electrical stimulation (MES), we treated A549 cells with low-intensity direct current at 5 V applied for 10 min. MES did not induce cell cytotoxicity or the unfolded protein response (UPR). Interestingly, the expression of ubiquitinated proteins and heat shock...