p62-Nrf2 Regulatory Loop Mediates the Anti-Pulmonary Fibrosis Effect of Bergenin

• Main Authors: Qian Zeng (Author), Tingting Zhou (Author), Feiyan Zhao (Author), Dayan Xiong (Author), Bin He (Author), Qingzhong Hua (Author), Miao Lin (Author), Lang Deng (Author), Xiaoxue Sang (Author), Weixi Xie (Author), Jia Chen (Author), Zun Wang (Author), Lu Ren (Author), Ziqiang Luo (Author), Xiaoting Huang (Author), Wei Liu (Author), Siyuan Tang (Author)
• Format: Book
• Published: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Idiopathic pulmonary fibrosis (IPF) can severely disrupt lung function, leading to fatal consequences, and there is currently a lack of specific therapeutic drugs. Bergenin is an isocoumarin compound with lots of biological functions including antioxidant activity. This study evaluated the potential...