CRISPR-Cas9‒Based Genomic Engineering in Keratinocytes: From Technology to Application

• 主要な著者: Jos P.H. Smits (著者), Luca D. Meesters (著者), Berber G.W. Maste (著者), Huiqing Zhou (著者), Patrick L.J.M. Zeeuwen (著者), Ellen H. van den Bogaard (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2022-03-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

CRISPR-Cas9 is the most straightforward genome-editing tool to date. However, its implementation across disciplines is hampered by variable genome-editing efficiencies, reduced cell viability, and low success rates in obtaining clonal cell lines. This review aims to recognize all CRISPR-Cas9‒related...