Ghrelin transport across the blood-brain barrier can occur independently of the growth hormone secretagogue receptor

• Principais autores: Elizabeth M. Rhea (Autor), Therese S. Salameh (Autor), Sarah Gray (Autor), Jingjing Niu (Autor), William A. Banks (Autor), Jenny Tong (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2018-12-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Objective: The blood-brain barrier (BBB) regulates the entry of substrates and peptides into the brain. Ghrelin is mainly produced in the stomach but exerts its actions in the central nervous system (CNS) by crossing the BBB. Once present in the CNS, ghrelin can act in the hypothalamus to regulate f...