Characterization and functional analysis of the proteins Prohibitin 1 and 2 in Trypanosoma cruzi.

• Main Authors: Ana K Ibarrola-Vannucci (Author), Luis M De Pablos (Author), Lissette Retana-Moreira (Author), Alberto Cornet-Gomez (Author), Teresa Cruz-Bustos (Author), Alejandro G Schijman (Author), José L Ramírez (Author), Susana Vílchez (Author), Antonio Osuna (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Chagas disease is the third most important neglected tropical disease. There is no vaccine available, and only two drugs are generally prescribed for the treatment, both of which with a wide range of side effects. Our study of T. cruzi PHBs revealed a pleiotropic funct...