Development and validation of two bioanalysis methods for the determination of etimicin in human serum and urine by liquid chromatography-tandem mass spectrometry: Applications to a human pharmacokinetic and breakpoint study

• Главные авторы: Xinge Cui (Автор), Xin Zheng (Автор), Jianwei Ren (Автор), Hongzhong Liu (Автор), Yuan Jia (Автор), Aiguo Wu (Автор), Xiaohong Han (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Предметы: article
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Etimicin is a fourth-generation aminoglycoside antibiotic. It has potent activity and low toxicity when employed for the treatment of Gram-negative and Gram-positive bacterial infections. The pharmacokinetics of etimicin in humans have not been elucidated completely. Two liquid chromatography-tandem...