In silico mapping of the dynamic interactions and structure-activity relationship of flavonoid compounds against the immune checkpoint programmed-cell death 1 pathway

• Glavni autori: Geraldo Rodrigues Sartori (Autor), Aline de Oliveira Albuquerque (Autor), Andrielly Henriques Santos-Costa (Autor), Luca Milério Andrade (Autor), Diego da Silva Almeida (Autor), Eduardo Menezes Gaieta (Autor), Jean Vieira Sampaio (Autor), Vitória Taiana de Melo Lima Albuquerque (Autor), João Hermínio Martins Da Silva (Autor)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2022-12-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Flavonoids are a class of natural products widely available in medicinal and dietary plants. Their pharmacological use has shown the potential to reduce the risk of different types of cancer, among other prevalent diseases. Their molecular scaffold inhibits the PD-1/PD-L1 axis, an important pathway...