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Biodegradable Nanoparticles Mediated Co-delivery of Erlotinib (ELTN) and Fedratinib (FDTN) Toward the Treatment of ELTN-Resistant Non-small Cell Lung Cancer (NSCLC) via Suppression of the JAK2/STAT3 Signaling Pathway

Background: Erlotinib (ELTN)-based targeted therapy as first-line treatment for epidermal growth factor receptor (EGFR)-mutant lung cancers suffers from insufficient selectivity, side effects, and drug resistance, which poses critical challenges in the clinical setting. Acquired resistance of ELTN r...

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書誌詳細
主要な著者:	Donglai Chen (著者), Fuquan Zhang (著者), Jinhui Wang (著者), Hua He (著者), Shanzhou Duan (著者), Rongying Zhu (著者), Chang Chen (著者), Lichen Yin (著者), Yongbing Chen (著者)
フォーマット:	図書
出版事項:	Frontiers Media S.A., 2018-11-01T00:00:00Z.
主題:	article
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