Analytical characterization of coformulated antibodies as combination therapy

• Main Authors: Jun Kim (Author), Yoen Joo Kim (Author), Mingyan Cao (Author), Niluka De Mel (Author), Kenneth Miller (Author), Jared S. Bee (Author), Jihong Wang (Author), Xiangyang Wang (Author), Methal Albarghouthi (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

When two therapeutic agents are combined in a single formulation, i.e., coformulated, the quality and safety of the individual agents must be preserved. Here we describe an approach to evaluate the quality attributes of two individual monoclonal antibodies (mAbs), designated mAb-A and mAb-B, in cofo...