Analytical characterization of coformulated antibodies as combination therapy

• Главные авторы: Jun Kim (Автор), Yoen Joo Kim (Автор), Mingyan Cao (Автор), Niluka De Mel (Автор), Kenneth Miller (Автор), Jared S. Bee (Автор), Jihong Wang (Автор), Xiangyang Wang (Автор), Methal Albarghouthi (Автор)
• Формат: ‌
• Опубликовано: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Предметы: article
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When two therapeutic agents are combined in a single formulation, i.e., coformulated, the quality and safety of the individual agents must be preserved. Here we describe an approach to evaluate the quality attributes of two individual monoclonal antibodies (mAbs), designated mAb-A and mAb-B, in cofo...