Extracellular matrix marker LAMC2 targets ZEB1 to promote TNBC malignancy via up-regulating CD44/STAT3 signaling pathway

• Main Authors: Ding Wang (Author), Kailibinuer Keyoumu (Author), Rongji Yu (Author), Doudou Wen (Author), Hao Jiang (Author), Xinchun Liu (Author), Xiaotang Di (Author), Shubing Zhang (Author)
• Format: Book
• Published: BMC, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Triple negative breast cancer (TNBC) is a heterogeneous and aggressive disease characterized by a high risk of mortality and poor prognosis. It has been reported that Laminin γ2 (LAMC2) is highly expressed in a variety of tumors, and its high expression is correlated with cancer...