Dual-Functional Polymeric Micelles Co-Loaded with Antineoplastic Drugs and Tyrosine Kinase Inhibitor for Combination Therapy in Colorectal Cancer

• Main Authors: Ying-Hsia Shih (Author), Cheng-Liang Peng (Author), Ping-Fang Chiang (Author), Ming-Jium Shieh (Author)
• Formato: Libro
• Publicado: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

The aim of this research was to evaluate the receptor tyrosine kinase inhibitor Sunitinib combined with SN-38 in polymeric micelles for antitumor efficacy in colorectal cancer. First, SN-38 and Sunitinib co-loaded micelles were developed and characterized. We studied cell viability and cellular upta...