In Silico and In Vitro Identification of Pan-Coronaviral Main Protease Inhibitors from a Large Natural Product Library

The main protease (M<sup>pro</sup> or 3CL<sup>pro</sup>) in coronaviruses represents a promising specific drug target as it is essential for the cleavage of the virus polypeptide and has a unique cleavage site that does not exist in human host proteases. In this study, we exp...

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Main Authors: Nasim Shahhamzehei (Author), Sara Abdelfatah (Author), Thomas Efferth (Author)
Format: Book
Published: MDPI AG, 2022-03-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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