In Silico and In Vitro Identification of Pan-Coronaviral Main Protease Inhibitors from a Large Natural Product Library
The main protease (M<sup>pro</sup> or 3CL<sup>pro</sup>) in coronaviruses represents a promising specific drug target as it is essential for the cleavage of the virus polypeptide and has a unique cleavage site that does not exist in human host proteases. In this study, we exp...
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MDPI AG,
2022-03-01T00:00:00Z.
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