In Silico and In Vitro Identification of Pan-Coronaviral Main Protease Inhibitors from a Large Natural Product Library

• Asıl Yazarlar: Nasim Shahhamzehei (Yazar), Sara Abdelfatah (Yazar), Thomas Efferth (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2022-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The main protease (M^pro or 3CL^pro) in coronaviruses represents a promising specific drug target as it is essential for the cleavage of the virus polypeptide and has a unique cleavage site that does not exist in human host proteases. In this study, we exp...