Synthesis and Biological Evaluation of 1-(Diarylmethyl)-1<i>H</i>-1,2,4-triazoles and 1-(Diarylmethyl)-1<i>H</i>-imidazoles as a Novel Class of Anti-Mitotic Agent for Activity in Breast Cancer
We report the synthesis and biochemical evaluation of compounds that are designed as hybrids of the microtubule targeting benzophenone phenstatin and the aromatase inhibitor letrozole. A preliminary screening in estrogen receptor (ER)-positive MCF-7 breast cancer cells identified 5-((2<i>H<...
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Asıl Yazarlar: | , , , , , , , , , , , |
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Materyal Türü: | Kitap |
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MDPI AG,
2021-02-01T00:00:00Z.
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Internet
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Yer Numarası: |
A1234.567 |
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Kopya Bilgisi 1 | Kütüphanede |