Truncating mutation in TANC2 in a Chinese boy associated with Lennox-Gastaut syndrome: a case report

• Main Authors: Yang Tian (Author), Zhen Shi (Author), Chi Hou (Author), Wenjuan Li (Author), Xiuying Wang (Author), Haixia Zhu (Author), Xiaojing Li (Author), Wen-Xiong Chen (Author)
• Format: Book
• Published: BMC, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Lennox-Gastaut syndrome (LGS) is a severe epileptic encephalopathy that can be caused by brain malformations or genetic mutations. Recently, genome-wide association studies have led to the identification of novel mutations associated with LGS. The TANC2 gene, encodes a synaptic s...