High-grade serous carcinoma with discordant p53 signature: report of a case with new insight regarding high-grade serous carcinogenesis

• Главные авторы: Yuichiro Hatano (Автор), Shinya Fukuda (Автор), Hiroshi Makino (Автор), Hiroyuki Tomita (Автор), Ken-ichirou Morishige (Автор), Akira Hara (Автор)
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• Опубликовано: BMC, 2018-04-01T00:00:00Z.
• Предметы: article
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Abstract Background Although p53 signature, benign-appearing epithelial cells with p53 diffuse expression, is frequently found in the fallopian tubes, the clinical and pathological significance of this lesion in the case of high-grade serous carcinoma (HGSC) patients still remains unclear. Case pres...