Systems pharmacology of adiposity reveals inhibition of EP300 as a common therapeutic mechanism of caloric restriction and resveratrol for obesity

• Үндсэн зохиолчид: Yuhei eNishimura (Зохиогч), Shota eSasagawa (Зохиогч), Michiko eAriyoshi (Зохиогч), Sayuri eIchikawa (Зохиогч), Yasuhito eShimada (Зохиогч), Koki eKawaguchi (Зохиогч), Reiko eKawase (Зохиогч), Reiko eYamamoto (Зохиогч), Takuma eUehara (Зохиогч), Takaaki eYanai (Зохиогч), Ryoji eTakata (Зохиогч), Toshio eTanaka (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Frontiers Media S.A., 2015-09-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Both caloric restriction and resveratrol have beneficial effects on obesity. However, the biochemical pathways that mediate these beneficial effects might be complex and interconnected and have not been fully elucidated. To reveal the common therapeutic mechanism of caloric restriction and resveratr...