p53-Induced Autophagy Regulates Chemotherapy and Radiotherapy Resistance in Multidrug Resistance Cancer Cells

• Main Authors: Shumei Ma (Author), Dejuan Kong (Author), Xinxin Fu (Author), Lin Liu (Author), Yi Liu (Author), Chang Xue (Author), Zhujun Tian (Author), Lan Li (Author), Xiaodong Liu (Author)
• Format: Book
• Published: SAGE Publishing, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background Multidrug resistance (MDR), a major problem in oncology therapy, limits the effectiveness of anticancer drugs. Although p53 functions as a tumor suppressor, the associations between p53 status, autophagy, and MDR are complicated and conditional. Method  In this report, p53-null human ovar...