Genetic Linkage Analysis of DFNB4, DFNB28, DFNB93 Loci in Autosomal Recessive Non-syndromic Hearing Loss: Evidence for Digenic Inheritance in GJB2 and GJB3 Mutations

• Main Authors: Marzieh NASERI (Author), Masoud AKBARZADEHLALEH (Author), Marjan MASOUDI (Author), Najmeh AHANGARI (Author), Ali Akbar POURSADEGH ZONOUZI (Author), Ahmad POURSADEGH ZONOUZI (Author), Leila SHAMS (Author), Azim NEJATIZADEH (Author)
• Formato: Livro
• Publicado em: Tehran University of Medical Sciences, 2017-12-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Background: Autosomal recessive non-syndromic hearing loss (ARNSHL) a most frequent hereditary type of hearing impairment, exhibit tremendous genetic heterogeneity. We aimed to determine the contribution of three common DFNB loci (DFNB4, DFNB28, and DFNB93), and mutation analysis of Gap Junction Bet...