Co-Treatment With Resveratrol and FGF1 Protects Against Acute Liver Toxicity After Doxorubicin Treatment via the AMPK/NRF2 Pathway

• Main Authors: Xianchou Xu (Author), Qingbo Liu (Author), Jiahao Li (Author), Mengjie Xiao (Author), Ting Gao (Author), Xiaohui Zhang (Author), Guangping Lu (Author), Jie Wang (Author), Yuanfang Guo (Author), Peinan Wen (Author), Junlian Gu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Doxorubicin (DOX), an anthracycline type of chemotherapy, is an effective therapy for several types of cancer, but serious side effects, such as severe hepatotoxicity, limit its use currently. Accordingly, an effective therapeutic strategy to prevent DOX-related hepatotoxicity is urgently needed. Th...