Tofacitinib Represses the Janus Kinase-Signal Transducer and Activators of Transcription Signalling Pathway in Keratinocytes

• Asıl Yazarlar: Ankit Srivastava (Yazar), Mona Ståhle (Yazar), Andor Pivarcsi (Yazar), Enikö Sonkoly (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Medical Journals Sweden, 2018-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Tofacitinib is a Janus kinase (JAK) inhibitor, which has shown efficacy in treating psoriasis. The mode of action of tofacitinib is not completely understood but it has been thought to be mediated by the inhibition of CD4+ T-cell activation. Here, we investigated whether the molecular targets of tof...