Modelling of chromatographic and electrophoretic behaviour of imidazoline and alpha adrenergic receptors ligands under different acid-base conditions

• Main Authors: Slavica Oljacic (Author), Mitja Križman (Author), Marija Popovic-Nikolic (Author), Irena Vovk (Author), Katarina Nikolic (Author), Danica Agbaba (Author)
• Format: Book
• Published: International Association of Physical Chemists (IAPC), 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and Purpose: The ligands of the imidazoline and α-adrenergic receptors are mainly imidazoline and guanidine derivatives, known as centrally-acting antihypertensives and compounds with potential use in various neurological disorders. The extent of their ionisation has a major influence on...