Polymorphisms in PI3K/AKT genes and gene‑smoking interaction are associated with susceptibility to tuberculosis

• Main Authors: Chunli Wu (Author), Huixia Liu (Author), Ying Lin (Author), Rongjing An (Author), Mian Wang (Author), Hua Zhong (Author), Hengzhong Yi (Author), Qiaozhi Wang (Author), Hongzhuan Tan (Author), Lizhang Chen (Author), Jing Deng (Author), Mengshi Chen (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AbstractBackground Phosphatidylinositol 3-kinase (PI3K) and protein kinase B (AKT) are involved in the clearance of Mycobacterium tuberculosis (MTB) by macrophages.Aim This study aimed to investigate the effects of polymorphisms in the PI3K/AKT genes and the gene-smoking interaction on susceptibilit...