The Effect of Shionone on Sepsis-Induced Acute Lung Injury by the ECM1/STAT5/NF-κB Pathway

• Main Authors: Yi Song (Author), Qian Wu (Author), Huojun Jiang (Author), Aihao Hu (Author), Lingqi Xu (Author), Caiping Tan (Author), Biao Zhang (Author), Rongming Yu (Author), Yizhen Qiu (Author), Xin Wang (Author), Wenzhong Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: The purpose of the present study was to estimate the effect of shionone (SHI) on sepsis-induced acute lung injury (ALI).Methods: The cecal ligation and puncture (CLP) surgery was performed to induce sepsis in mice. Pulmonary hematoxylin and eosin staining, the wet/dry ratio, myeloperoxidase...