Exosomal MicroRNA-126 from RIPC Serum Is Involved in Hypoxia Tolerance in SH-SY5Y Cells by Downregulating DNMT3B

• Main Authors: Junhe Cui (Author), Na Liu (Author), Zhehan Chang (Author), Yongsheng Gao (Author), Mulan Bao (Author), Yabin Xie (Author), Wenqiang Xu (Author), Xiaolei Liu (Author), Shuyuan Jiang (Author), You Liu (Author), Rui Shi (Author), Wei Xie (Author), Xiaoe Jia (Author), Jinghua Shi (Author), Changhong Ren (Author), Kerui Gong (Author), Chunyang Zhang (Author), Rengui Bade (Author), Guo Shao (Author), Xunming Ji (Author)
• Format: Book
• Published: Elsevier, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ischemic tolerance in the brain can be induced by transient limb ischemia, and this phenomenon is termed remote ischemic preconditioning (RIPC). It still remains elusive how this transfer of tolerance occurs. Exosomes can cross the blood-brain barrier, and some molecules may transfer neuroprotective...