Preferential expression of cytochrome CYP CYP2R1 but not CYP1B1 in human cord blood hematopoietic stem and progenitor cells

• Main Authors: Shuoqi Xu (Author), Zhihua Ren (Author), Yanan Wang (Author), Xinxin Ding (Author), Yongping Jiang (Author)
• Format: Bog
• Udgivet: Elsevier, 2014-12-01T00:00:00Z.
• Fag: article
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Cytochrome P450 (CYP) enzymes metabolize numerous endogenous substrates, such as retinoids, androgens, estrogens and vitamin D, that can modulate important cellular processes, including proliferation, differentiation and apoptosis. The aim of this study is to characterize the expression of CYP genes...