Notoginsenoside R1 Improves Cerebral Ischemia/Reperfusion Injury by Promoting Neurogenesis via the BDNF/Akt/CREB Pathway

• Main Authors: Ting Zhu (Author), Lei Wang (Author), Weijie Xie (Author), Xiangbao Meng (Author), Yicheng Feng (Author), Guibo Sun (Author), Xiaobo Sun (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Notoginsenoside R1 (R1), a major component isolated from P. notoginseng, is a phytoestrogen that exerts many neuroprotective effects in a rat model of ischemic stroke. However, its long-term effects on neurogenesis and neurological restoration after ischemic stroke have not been investigated. The ai...