Interleukin-6, -8, and TGF-β Secreted from Mesenchymal Stem Cells Show Functional Role in Reduction of Telomerase Activity of Leukemia Cell Via Wnt5a/β-Catenin and P53 Pathways

• Main Authors: Ezzatollah Fathi (Author), Behnaz Valipour (Author), Zohreh Sanaat (Author), Hojjatollah Nozad Charoudeh (Author), Raheleh Farahzadi (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: The effect of mesenchymal stem cells (MSCs) on the immortality features of malignant cells, such as hematologic cancerous cells, are controversial, and the associated mechanisms are yet to be well understood. The aim of the present study was to investigate the in vitro effect of bone marrow...