The challenges of oral drug delivery via nanocarriers

• Hoofdauteurs: Jonas Reinholz (Auteur), Katharina Landfester (Auteur), Volker Mailänder (Auteur)
• Formaat: Boek
• Gepubliceerd in: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

The oral application of pharmaceuticals is unarguably the most convenient method of application. Especially for protein- or peptide-based drugs, however, the effectiveness is significantly reduced due to enzymatic digestion in the stomach as well as a poor bioavailability in the small intestine. For...