In Vitro Study of Licorice on IL-1β-Induced Chondrocytes and In Silico Approach for Osteoarthritis

• Main Authors: Akhtar Ali (Author), YoungJoon Park (Author), Jeonghoon Lee (Author), Hyo-Jin An (Author), Jong-Sik Jin (Author), Jong-Hyun Lee (Author), Jaeki Chang (Author), Dong-Keun Kim (Author), Bonhyuk Goo (Author), Yeon Cheol Park (Author), Kang-Hyun Leem (Author), Shin Seong (Author), Wonnam Kim (Author)
• Format: Book
• Published: MDPI AG, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteoarthritis (OA) is a common degenerative joint disorder that affects joint function, mobility, and pain. The release of proinflammatory cytokines stimulates matrix metalloproteinases (MMPs) and aggrecanase production which further induces articular cartilage degradation. Hypertrophy-like changes...