Transcriptome Profiling of Neovascularized Corneas Reveals miR-204 as a Multi-target Biotherapy Deliverable by rAAVs

• Main Authors: Yi Lu (Author), Phillip W.L. Tai (Author), Jianzhong Ai (Author), Dominic J. Gessler (Author), Qin Su (Author), Xieyi Yao (Author), Qiang Zheng (Author), Phillip D. Zamore (Author), Xun Xu (Author), Guangping Gao (Author)
• Format: Book
• Published: Elsevier, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Corneal neovascularization (NV) is the major sight-threatening pathology caused by angiogenic stimuli. Current drugs that directly target pro-angiogenic factors to inhibit or reverse the disease require multiple rounds of administration and have limited efficacies. Here, we identify potential anti-a...