Advancing 6-bromo-7-[11C]methylpurine to clinical use: improved regioselective radiosynthesis, non-clinical toxicity data and human dosimetry estimates

Advancing 6-bromo-7-[11C]methylpurine to clinical use: improved regioselective radiosynthesis, non-clinical toxicity data and human dosimetry estimates

Abstract Background 6-Bromo-7-[11C]methylpurine ([11C]BMP) is a radiotracer for positron emission tomography (PET) to measure multidrug resistance-associated protein 1 (MRP1) transport activity in different tissues. Previously reported radiosyntheses of [11C]BMP afforded a mixture of 7- and 9-[11C]m...

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Main Authors: Severin Mairinger (Author), Matthias Jackwerth (Author), Ondřej Soukup (Author), Matthias Blaickner (Author), Clemens Decristoforo (Author), Lukas Nics (Author), Jens Pahnke (Author), Marcus Hacker (Author), Markus Zeitlinger (Author), Oliver Langer (Author)
Format: Book
Published: SpringerOpen, 2024-04-01T00:00:00Z.
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3rd Floor Main Library

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