Nitazoxanide: A Drug Repositioning Compound with Potential Use in Chagas Disease in a Murine Model

• Principais autores: Minerva Arce-Fonseca (Autor), Rodolfo Andrés Gutiérrez-Ocejo (Autor), José Luis Rosales-Encina (Autor), Alberto Aranda-Fraustro (Autor), Juan José Cabrera-Mata (Autor), Olivia Rodríguez-Morales (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2023-06-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Chagas disease (ChD), caused by <i>Trypanosoma cruzi</i>, is the most serious parasitosis in the western hemisphere. Benznidazole and nifurtimox, the only two trypanocidal drugs, are expensive, difficult to obtain, and have severe side effects. Nitazoxanide has shown to be effective agai...