Bisphosphonate-Related Osteonecrosis of the Jaw: A Review of the Literature

• Main Authors: Eder Alberto Sigua-Rodriguez (Author), Renato da Costa Ribeiro (Author), Ana Caroline Ramos de Brito (Author), Natalia Alvarez-Pinzon (Author), José Ricardo de Albergaria-Barbosa (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bisphosphonates (BPs) are a class of drugs used to treat osteoporosis and malignant bone metastasis. BPs show high binding capacity to the bone matrix, especially in sites of active bone metabolism. The American Society for Bone and Mineral Research defines BRONJ as "an area of exposed bone in...