Baicalein Inhibits Benzo[a]pyrene-Induced Toxic Response by Downregulating Src Phosphorylation and by Upregulating NRF2-HMOX1 System

Benzo[a]pyrene (BaP), a major environmental pollutant, activates aryl hydrocarbon receptor (AHR), induces its cytoplasmic-to-nuclear translocation and upregulates the production of cytochrome P450 1A1 (CYP1A1), a xenobiotic metabolizing enzyme which metabolize BaP. The BaP-AHR-CYP1A1 axis generates...

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Main Authors: Yuka Tanaka (Author), Takamichi Ito (Author), Gaku Tsuji (Author), Masutaka Furue (Author)
Format: Book
Published: MDPI AG, 2020-06-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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