Modulation of Keap1/Nrf2/ARE Signaling Pathway by Curcuma- and Garlic-Derived Hybrids

• Main Authors: Melania Maria Serafini (Author), Michele Catanzaro (Author), Francesca Fagiani (Author), Elena Simoni (Author), Roberta Caporaso (Author), Marco Dacrema (Author), Irene Romanoni (Author), Stefano Govoni (Author), Marco Racchi (Author), Maria Daglia (Author), Michela Rosini (Author), Cristina Lanni (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nrf2 is a basic leucine zipper transcription factor that binds to the promoter region of the antioxidant response element (ARE), inducing the coordinated up-regulation of antioxidant and detoxification genes. We recently synthesized a set of new molecules by combining the functional moieties of curc...