FM-CATH, A Novel Cathelicidin From Fejervarya Multistriata, Shows Therapeutic Potential for Treatment of CLP-Induced Sepsis

• Main Authors: Jiena Wu (Author), Haiyun Zhang (Author), Xiaoxin Chen (Author), Jinwei Chai (Author), Yunrui Hu (Author), Weichen Xiong (Author), Wancheng Lu (Author), Maolin Tian (Author), Xin Chen (Author), Xueqing Xu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sepsis is an exacerbated inflammatory reaction induced by severe infection. As important defensive molecules in innate immunity, several AMPs are reported to prevent septic shock. In this study, we characterized a novel cathelicidin, FM-CATH, from the frog skin of F. multistriata. FM-CATH was found...