Polymorphisms and haplotypes in the promoter of the TNF-α gene are associated with disease severity of severe fever with thrombocytopenia syndrome in Chinese Han population.

• Hoofdauteurs: Bo Xing (Auteur), Xiao-Kun Li (Auteur), Shao-Fei Zhang (Auteur), Qing-Bin Lu (Auteur), Juan Du (Auteur), Pan-He Zhang (Auteur), Zhen-Dong Yang (Auteur), Ning Cui (Auteur), Chen-Tao Guo (Auteur), Wu-Chun Cao (Auteur), Xiao-Ai Zhang (Auteur), Wei Liu (Auteur)
• Formaat: Boek
• Gepubliceerd in: Public Library of Science (PLoS), 2018-06-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease that is caused by a novel bunyavirus, SFTSV. We assessed whether the single nucleotide polymorphisms (SNPs) in the tumor necrosis factor-alpha (TNF-α) were associated with risk to severity of SFTS. Five TNF-α SNPs (...