Myopalladin promotes muscle growth through modulation of the serum response factor pathway

• Main Authors: Maria Carmela Filomena (Author), Daniel L. Yamamoto (Author), Marco Caremani (Author), Vinay K. Kadarla (Author), Giuseppina Mastrototaro (Author), Simone Serio (Author), Anupama Vydyanath (Author), Margherita Mutarelli (Author), Arcamaria Garofalo (Author), Irene Pertici (Author), Ralph Knöll (Author), Vincenzo Nigro (Author), Pradeep K. Luther (Author), Richard L. Lieber (Author), Moriah R. Beck (Author), Marco Linari (Author), Marie‐Louise Bang (Author)
• Format: Book
• Published: Wiley, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Myopalladin (MYPN) is a striated muscle‐specific, immunoglobulin‐containing protein located in the Z‐line and I‐band of the sarcomere as well as the nucleus. Heterozygous MYPN gene mutations are associated with hypertrophic, dilated, and restrictive cardiomyopathy, and homozygous...