Effect of Daridorexant on the Pharmacokinetics of Midazolam, and on the Pharmacokinetics and Pharmacodynamics of Warfarin in Healthy Male Subjects

Abstract Background and Objectives Daridorexant, a dual orexin receptor antagonist was recently approved for the treatment of insomnia at doses up to 50 mg once per night. This study investigated the effect of single-dose and multiple-dose daridorexant 50 mg at steady state on the pharmacokinetics (...

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Main Authors: Isabelle Zenklusen (Author), Jasper Dingemanse (Author), Christian Reh (Author), Martine Gehin (Author), Priska Kaufmann (Author)
Format: Book
Published: Adis, Springer Healthcare, 2024-03-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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