Humanized yeast genetic interaction mapping predicts synthetic lethal interactions of FBXW7 in breast cancer
Abstract Background Synthetic lethal interactions (SLIs) that occur between gene pairs are exploited for cancer therapeutics. Studies in the model eukaryote yeast have identified ~ 550,000 negative genetic interactions that have been extensively studied, leading to characterization of novel pathways...
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| Main Authors: | , , , , , , |
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| Format: | Book |
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BMC,
2019-07-01T00:00:00Z.
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