Preformulation Study of Electrospun Haemanthamine-Loaded Amphiphilic Nanofibers Intended for a Solid Template for Self-Assembled Liposomes

• Main Authors: Khan Viet Nguyen (Author), Ivo Laidmäe (Author), Karin Kogermann (Author), Andres Lust (Author), Andres Meos (Author), Duc Viet Ho (Author), Ain Raal (Author), Jyrki Heinämäki (Author), Hoai Thi Nguyen (Author)
• Format: Book
• Published: MDPI AG, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Haemanthamine (HAE) has been proven as a potential anticancer agent. However, the therapeutic use of this plant-origin alkaloid to date is limited due to the chemical instability and poorly water-soluble characteristics of the agent. To overcome these challenges, we developed novel amphiphilic elect...