LANCL1 binds abscisic acid and stimulates glucose transport and mitochondrial respiration in muscle cells via the AMPK/PGC-1α/Sirt1 pathway

• Main Authors: Sonia Spinelli (Author), Giulia Begani (Author), Lucrezia Guida (Author), Mirko Magnone (Author), Denise Galante (Author), Cristina D'Arrigo (Author), Claudia Scotti (Author), Luisa Iamele (Author), Hugo De Jonge (Author), Elena Zocchi (Author), Laura Sturla (Author)
• Format: Book
• Published: Elsevier, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Abscisic acid (ABA) is a plant hormone also present and active in animals. In mammals, ABA regulates blood glucose levels by stimulating insulin-independent glucose uptake and metabolism in adipocytes and myocytes through its receptor LANCL2. The objective of this study was to investigate...